Bioware just announced the system requirements for the PC version of their RPG Mass Effect. 

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Minimum System Requirements
Operating System:
Windows XP or Vista

Processor:
2.4+GHZ Intel or 2.0+GHZ AMD

Memory:
1 Gigabyte Ram (XP)
2 Gigabyte Ram (Vista)

Video Card:
NVIDIA GeForce 6 series(6800GT or better)
ATI 1300XT or better (X1550, X1600 Pro and HD2400 are below minimum system requirements)

Hard Drive Space:
12 Gigabytes

Sound Card:
DirectX 9.0c compatible sound card and drivers
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Recommended System Requirements
Operating System:
Windows XP or Vista

Processor:
2.6+GHZ Intel or 2.4+GHZ AMD

Memory:
2 Gigabyte Ram

Video Card:
NVIDIA GeForce 7900 GTX or higher.
ATI X1800 XL series or higher

Hard Drive Space:
12 Gigabytes

Sound Card:
DirectX 9.0c compatible sound card and drivers - 5.1 sound card recommended

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Additional Note from Derek French:

The Mass Effect Config program will automatically adjust your settings on first run, to attempt to give you an optimal play experience. As with all PC games, computer performance varies from system to system and adjustments can be made via the Config or through the in-game options to tailor your experience.